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Table 2 Association between MMP1 genotype and MMP1 levels

From: Genetic variants associated with circulating MMP1 levels near matrix metalloproteinase genes on chromosome 11q21-22 in Taiwanese: interaction with obesity

MMP1 genotype

MMP1 levels

P value

Adjusted P value

rs11226373 AA

536.6 ± 1333.4 (376)

0.111

0.555

 AG

321.7 ± 632.8 (120)

  

 GG

838.0 ± 1898.8 (12)

  

 AA

536.6 ± 1333.4 (376)

0.036

0.180

 AG + GG

368.6 ± 829.9 (132)

  

rs1799750 2G/2G

323.2 ± 794.7 (206)

1.5x10-4

7.5 x10-4

 2G/1G

543.9 ± 1294.1 (242)

  

 1G/1G

895.5 ± 1921.5 (58)

  

 2G/2G

323.2 ± 794.7 (206)

1.3x10-4

6.5 x10-4

 2G/1G + 1G/1G

611.9 ± 1439.8 (300)

  

rs1144393 TT

482.6 ± 1222.6 (428)

0.334

1

 TC

552.0 ± 1238.8 (80)

  

 CC

380.8 (1)

  

 TT

482.6 ± 1222.6 (428)

0.360

1

 TC + CC

549.9 ± 1231.1 (81)

  

rs514921 AA

454.9 ± 1122.9 (405)

0.905

1

 AG

667.9 ± 1601.6 (97)

  

 GG

336.4 ± 260.2 (6)

  

 AA

454.9 ± 1122.9 (405)

0.923

1

 AG + GG

648.5 ± 1556.8 (103)

  

rs495366 AA

299.7 ± 729.6 (174)

2.57x10-5

1.29 x10-4

 AG

561.7 ± 1352.7 (242)

  

 GG

683.6 ± 1547.7 (91)

  

 AA

299.7 ± 729.6 (174)

1.95x10-5

9.75 x10-5

 AG + GG

594.9 ± 1407.3 (333)

  
  1. P value, adjusted for age, sex, BMI, and smoking status.
  2. Adjusted P values were computed by the Bonferroni method.