Skip to main content

Table 2 Association between SNPs MC4R rs17782313, NEGR1 rs2815752, ENPP1 rs7754561, NPC1 rs1805081, GNPDA2 rs10938397 and FTO rs1421085, and obesity in Mexican children

From: Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4Rgenes to obesity in Mexican children

Locus SNP RA* Cases/ N RAF OR P  
Controls (%) [95% CI]  
    Lean children 949 74.4 - -  
NEGR1 rs2815752 A       
    Obese children 514 77.6 1.18 [0.99;1.41] 0.068  
    Lean children 949 74.6 - -  
NPC1 rs1805081 A       
    Obese children 514 74.2 1.02 [0.85;1.21] 0.845  
    Lean children 949 48.6 - -  
ENPP1 rs7754561 G       
    Obese children 514 44.2 0.84 [0.72;0.97] 0.020  
    Lean children 949 7.3 - -  
MCR4 rs17782313 C       
    Obese children 514 9.8 1.40 [1.06;1.83] 0.016  
    Lean children 949 32.2 - -  
GNPDA2 rs10938397 G       
    Obese children 514 38.0 1.30 [1.11;1.53] 1.34 × 10 -3  
    Lean children 949 19.1 - -  
FTO rs1421085 C       
    Obese children 514 21.1 1.13 [0.93;1.38] 0.228  
  1. *We noted the risk-alleles reported in European populations.
  2. RA, risk-allele; RAF, risk-allele frequency; OR, odds ratio; CI, confidence interval; P, P-Value.