Skip to main content

Table 2 Genotypic distribution of the FTO analysed polymorphisms and its association with obesity

From: Influence of FTO variants on obesity, inflammation and cardiovascular disease risk biomarkers in Spanish children: a case–control multicentre study

   Case Control   Minor Allele    
Polymorphism Allele 1/allele 2 11 12 22 11 12 22 Minor allele Case Control OR (95% CI) P P corr*
rs12445162 G/A 253 39 0 203 37 2 A 0.066 0.085 0.63 (0.35 - 1.11) 0.108 1
rs11075986 C/G 249 42 1 200 38 4 G 0.075 0.097 1.07 (0.80 - 1.44) 0.630 1
rs7203521 A/G 110 143 39 90 116 36 G 0.381 0.388 0.93 (0.68 - 1.28) 0.667 1
rs1861868 A/G 85 155 52 63 118 60 G 0.453 0.494 0.78 (0.58 - 1.06) 0.108 1
rs11643744 A/G 157 117 18 123 104 14 G 0.268 0.278 0.86 (0.61 - 1.22) 0.404 1
rs9928094 A/G 67 149 75 88 114 40 G 0.511 0.398 1.66 (1.22 - 2.24) 0.0009 0.018
rs9930333 T/G 67 150 74 87 112 41 G 0.511 0.398 1.64 (1.21 - 2.22) 0.001 0.023
rs10852521 C/T 104 139 49 64 116 61 T 0.410 0.496 0.67 (0.49 - 0.90) 0.008 0.327
rs7205986 A/G 68 151 72 70 111 61 G 0.505 0.483 0.78 (0.46 - 1.34) 0.369 1
rs9935401 G/A 72 150 69 95 111 33 A 0.419 0.370 1.76 (1.29 - 2.41) 0.0003 0.004
rs9939609 T/A 72 149 69 90 118 33 A 0.491 0.377 1.73 (1.26 - 2.37) 0.0006 0.009
rs3826169 T/C 170 102 20 151 81 10 C 0.245 0.210 1.32 (0.92 - 1.89) 0.132 1
rs8061518 A/G 159 107 22 95 108 32 G 0.262 0.365 0.56 (0.40 - 0.78) 0.0006 0.025
rs17818902 T/G 162 107 22 145 84 13 G 0.261 0.227 1.19 (0.84 - 1.67) 0.329 1
rs7190053 C/T 190 87 13 165 67 7 T 0.196 0.172 1.21 (0.82 - 1.78) 0.338 1
rs2111114 A/G 175 107 10 151 81 9 G 0.219 0.203 1.19 (0.82 - 1.74) 0.362 1
rs8044353 G/A 259 31 1 219 23 0 A 0.056 0.047 1.21 (0.61 - 2.39) 0.589 1
rs10521303 C/A 91 151 48 64 133 42 A 0.400 0.436 0.84 (0.62 - 1.15) 0.284 1
rs1558756 C/T 86 152 54 69 132 41 T 0.441 0.443 1.14 (0.83 - 1.57) 0.421 1
rs16952623 T/C 215 72 3 181 58 2 C 0.134 0.128 0.98 (0.62 - 1.56) 0.930 1
rs16952624 C/T 289 1 0 242 0 0 T 0.002 0.000    1
rs2111113 G/C 247 45 0 208 30 2 C 0.079 0.068 1.00 (0.56 - 1.78) 0.996 1
rs10852525 G/A 229 59 1 194 41 5 A 0.105 0.105 0.89 (0.55 - 1.45) 0.641 1
rs7194336 G/T 98 144 50 63 131 48 T 0.418 0.470 0.74 (0.55 - 1.01) 0.053 1
rs7203181 C/A 142 111 39 101 109 32 A 0.329 0.356 0.88 (0.65 - 1.19) 0.412 1
rs6499656 G/C 218 67 7 189 48 5 C 0.140 0.121 1.30 (0.84 - 2.03) 0.237 1
rs7191513 G/A 98 145 49 82 110 50 A 0.418 0.441 0.96 (0.72 - 1.30) 0.805 1
rs7194907 T/C 81 153 57 65 105 67 C 0.458 0.509 0.87 (0.64 - 1.18) 0.370 1
rs8056299 A/G 104 140 47 77 116 49 G 0.402 0.441 0.84 (0.62 - 1.14) 0.255 1
rs17225435 A/G 225 61 6 194 46 2 G 0.122 0.104 1.51 (0.93 - 2.46) 0.093 1
rs8049235 G/A 100 156 34 91 108 43 A 0.383 0.396 1.01 (0.74 - 1.59) 0.930 1
rs7199716 C/T 101 146 44 91 116 35 T 0.402 0.384 0.91 (0.67 - 1.24) 0.547 1
rs13334214 C/T 178 102 6 155 71 13 T 0.198 0.204 1.07 (0.74 - 1.57) 0.710 1
rs7194243 C/T 180 93 19 147 87 8 T 0.227 0.214 0.82 (0.57 - 1.18) 0.295 1
rs1136002 T/C 135 130 27 109 111 22 C 0.316 0.320 0.90 (0.66 - 1.24) 0.529 1
rs4784351 A/G 154 113 20 122 96 16 G 0.268 0.275 0.92 (0.65 - 1.28) 0.612 1
rs2540781 C/A 225 54 13 190 47 5 A 0.136 0.119 0.87 (0.57 - 1.32) 0.507 1
rs8049933 C/T 231 52 7 195 41 4 T 0.115 0.103 0.83 (0.52 - 1.32) 0.425 1
rs1558687 C/T 169 107 15 134 92 14 T 0.233 0.250 0.94 (0.67 - 1.33) 0.738 1
rs2075202 T/G 277 14 1 231 11 0 G 0.026 0.023 0.69 (0.25 - 1.88) 0.469 1
rs7200579 C/G 257 33 2 216 25 1 G 0.065 0.055 0.91 (0.50 - 1.68) 0.772 1
rs697771 C/T 102 137 53 72 127 43 T 0.413 0.443 1.00 (0.74 - 1.36) 0.985 1
rs12596638 G/A 221 66 4 176 61 5 A 0.126 0.150 0.99 (0.64 - 1.53) 0.979 1
rs1008400 C/T 81 148 61 67 132 43 T 0.469 0.451 0.97 (0.71 - 1.32) 0.860 1
rs12932373 C/T 214 76 2 175 61 3 T 0.136 0.139 0.77 (0.49 - 1.21) 0.261 1
rs2689248 C/A 79 153 59 64 113 63 A 0.463 0.492 0.79 (0.59 - 1.07) 0.124 1
rs17833492 C/A 140 127 24 106 112 23 A 0.296 0.322 0.88 (0.63 - 1.22) 0.437 1
  1. CI: confidence interval; OR: odds ratio. The OR was adjusted for age and sex under the additive model. *P values after Bonferroni correction. SNPs are ordered according to their genomic position.
\