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Table 3 Association between minor ACE2 alleles and blood pressure differences among males (NDIT Study, 1999–2005)

From: The association between the angiotensin-converting enzyme-2 gene and blood pressure in a cohort study of adolescents

 

SBP, mmHg

DBP, mmHg

 

Beta (Confidence interval)1

Beta (Confidence interval)1

SNP2

French Canadian

European

Other

French Canadian

European

Other

rs2074192

−2.65 (−7.3, 2.0)

−3.32 (−6.1, -0.6)3

1.57 (−3.5, 6.6)

0.41 (−2.0, 2.8)

−2.32 (−3.8, -0.8)4

−1.18 (−4.1, 1.7)

rs233575

−1.05 (−5.3, 3.2)

3.59 (0.8, 6.4)5

−1.05 (−5.9, 3.8)

−2.88 (−5.0. -0.8)6

2.42 (0.8, 4.0)7

−1.24 (−4.0, 1.6)

rs2158083

−1.85 (−6.0, 2.3)

3.40 (0.6-6.2)8

−0.32 (−5.2, 4.6)

−2.66 (−4.8. -0.6)9

1.33 (−0.3-2.9)

−0.20 (−3.0, 2.6)

rs1978124

−2.01 (−6.0, 2.0)

2.00 (−0.8, 4.8)

1.79 (−3.0, 6.6)

−1.29 (−3.3, 0.8)

0.73 (−0.9, 2.4)

0.90 (−1.9, 3.7)

  1. 1Adjusted for height, and whether or not the participant was overweight or obese; 2Reference groups were the major genotypes in accordance with dbSNP database: G for rs2074192 and rs1978124; T for rs233575 and rs2158083; 3 p-value=0.02; 4 p-value=0.003; 5 p-value=0.01; 6 p-value=0.001; 7 p-value=0.003; 8 p-value=0.02; 9 p-value=0.01.
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BMC Medical Genetics

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