Skip to main content

Table 2 Chromosome 22 status by iFISH vs SNP-arrays performed in 15/20 sporadic meningiomas

From: Association between mutation of the NF2gene and monosomy 22 in menopausal women with sporadic meningiomas

Tumor iFISH Karyotype Chromosome 22 status by SNP arrays* (n = 6206)
ID Chromosome 22 status Copy number values N. of SNPs with LOH/N. of informative SNPs (%)
M20 −22q −22 1.35 (1.01-1.93) 108 / 1326 (8%)
M18 −22q −22 1.19 (0.76-1.59) 365 / 1131 (32%)
M15 Complex & -22q −22 1.30 (0,85-2,03) 454 / 1158 (39%)
M14 −22q −22 1.34 (0.95-1.77) 80 / 1472 (5%)
M13 −22q −22 1.24 (0.92-1.8) 920 / 1188 (77%)
M11 Complex & -22q −22 1.20 (0.91-1.91) 694 / 1043 (67%)
M16 −22q −22 1.27 (0.81-1.75) 209 / 1340 (16%)
M7 −22q,-Y −22 1.52 (1.08-2.14) 18 / 1505 (1%)
M12 Complex & del(22q) del(22q11.22-qter) 1.50 (0.98-2) 19 / 1683 (2%)
M6 Complex & del(22q) del(22q11.22-qter) 1.34 (0.8-2.55) 763 / 1195 (64%)
M19 Complex Diploid 1.58 (1.12-2.06) 7 / 1630 (0.4%)
M10 Complex Diploid 1.71 (1.09-2.31) 9 / 1770 (0.5%)
M9 Diploid Diploid 1.75 (1.27-2.32) 3 / 1712 (0.2%)
M8 Diploid Diploid 1.92 (1.6-2.39) 5 / 1681 (0.3%)
M5 Diploid Diploid 1.79 (1.28-2.3) 3 / 1696 (0.2%)
  1. *LOH and copy number analyses involved 6206 SNP localized along the entire chromosome 22.
  2. iFISH interphase fluorescence in situ hybridization, SNP single nucleotide polymorphism, LOH loss of heterozigosity.