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Table 5 Influence of the HU use in SCA patients with the Bantu/Benin haplotype

From: Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia

Modulators Bantu/Benin (+HU) Bantu/Benin (−HU) P values*
n = 06 n = 04
Hb F ( % ) 17.41 ± 3.10 6.67 ± 4.37 0.0069#
TBARS (ng/mL) 1066.26 ± 495.09 1815.50 ± 334.80 0.0303#
TEAC (mM) 2.02 ± 0.16 2.08 ± 0.18 0.6124
GST (U/mL) 1.49 ± 0.62 1.27 ± 0.63 0.5925
CAT (U/mL) 2294.01 ± 297.29 1842.42 ± 397.81 0.0725
GSH (μM) 0.62 ± 0.37 0.84 ± 0.62 0.4981
  1. (−HU) patients not treated with HU. (+HU) patients treated with HU.
  2. *Comparisons were made by Mann–Whitney test.
  3. #Indicates statistical difference (p < 0.05).