Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia

BMC Medical Genetics

Table 2 Analysis of the age and gender interference on the biochemical markers values in SCA patients

	Age^#		P values*	Gender^#		P values*
	≤ 20 years n = 09	> 20 years n = 19	P values*	Male n = 11	Female n = 17	P values*
TBARS (ng/mL)	1452.94 ± 699.00	1577.07 ± 539.85	0.4950	1345.94 ± 413.13	1660.90 ± 655.72	0.0719
TEAC (mM)	1.97 ± 0.21	2.03 ± 0.15	0.6737	2.01 ± 0.23	2.01 ± 0.12	0.7292
GST (U/mL)	1.77 ± 0.94	1.51 ± 0.49	0.2394	1.50 ± 0.56	1.64 ± 0.72	0.3757
CAT (U/mL)	1660.80 ± 525.41	1912.16 ± 517.83	0.0957	1831.30 ± 634.04	1831.40 ± 461.03	0.7524
GSH (μM)	0.74 ± 0.49	0.70 ± 0.39	0.3644	0.59 ± 0.52	0.79 ± 0.31	0.2791

*Comparisons were made by factorial ANOVA.
^#There were no significant interactions between independent variables: age and gender (p > 0.05).

ISSN: 1471-2350