Figure 1From: Dopamine-agonist responsive Parkinsonism in a patient with the SANDO syndrome caused by POLG mutation Findings of nerve biopsy (semithin section in blue toluidine) and muscle sections stained for cytochrome c oxidase (COX) and succinate dehydrogenase (SDH) reactions. a: Nerve biopsy shows loss of both small and large nerve fibers. b: Muscle biopsy shows several fibers with absence of COX activity (arrow) and marked mitochondrial proliferation, as shown by their strong SDH reaction.Back to article page