Gene | SNP | MAF | p for HWET | A/a | Allele-specific (unadjusted) | Allele-specific (adjusted) | ||
---|---|---|---|---|---|---|---|---|
p value | OR (95% CI) | p valueb | OR (95% CI) | |||||
GC | rs4588 | 0.31 | 0.30 | Ca/A | 0.003 △ | 0.587 (0.412-0.836) | 0.003 △ | 0.583 (0.409-0.833) |
rs7041 | 0.26 | 0.29 | T/Ga | 0.252 | 1.216 (0.867-1.705) | 0.167 | 1.272 (0.901-1.791) | |
rs222020 | 0.34 | 0.67 | T/Ca | 0.009 △ | 1.526 (1.117-2.085) | 0.009 △ | 1.517 (1.108-2.078) | |
rs2282679 | 0.32 | 0.22 | Aa/C | 0.010 △ | 0.636 (0.449-0.900) | 0.010 △ | 0.631 (0.444-0.895) | |
rs2298849 | 0.32 | 0.98 | T/Ca | 0.001 △ | 1.709 (1.250-2.338) | 0.001 △ | 1.722 (1.256-2.362) | |
CYP2R1 | rs10741657 | 0.43 | 0.25 | Ga/A | 0.019 △ | 1.467 (1.070-2.011) | 0.016 △ | 1.477 (1.075-2.030) |
rs10766197 | 0.45 | 0.36 | Ga/A | 0.374 | 0.855 (0.619-1.179) | 0.416 | 0.874 (0.632-1.209) | |
rs12794714 | 0.43 | 0.36 | G/Aa | 0.089 | 1.322 (0.968-1.804) | 0.075 | 1.330 (0.971-1.820) | |
rs1562902 | 0.47 | 0.46 | Ta/C | 0.120 | 1.279 (0.940-1.740) | 0.115 | 1.284 (0.941-1.751) | |
rs2060793 | 0.27 | 0.42 | Ga/A | 0.023 △ | 0.689 (0.502-0.944) | 0.019 △ | 0.684 (0.498-0.940) | |
DHCR7/NADSYN1 | rs3829251 | 0.28 | 0.59 | G/Aa | 0.297 | 1.204 (0.863-1.680) | 0.342 | 1.176 (0.841-1.645) |
rs12785878 | 0.49 | 0.13 | Ta/G | 1.000 | 0.993 (0.733-1.345) | 0.879 | 0.977 (0.719-1.326) |