Table 1 Characteristics and genotype data extracted from eligible studies
Study (Year) | Country | Ethnicity | Genotyping method | Glioma type | Mean age | Gender (% males) | |||
|---|---|---|---|---|---|---|---|---|---|
Felini (2007) | USA | Caucasian | PCR-RFLP | Mixed | No data | No data | |||
Cengiz (2008) | Turkey | Caucasian | PCR-RFLP | Mixed | 55.2 | 50.4 | |||
Kiuru (2008) | Finland | Caucasian | PCR-RFLP | Mixed | No data | 61.8 | |||
Liu (2009) | USA | Caucasian | Array | Mixed | No data | 56.8 | |||
Rajaraman (2010) | USA | Caucasian | Taqman Real Time | Mixed | 51.2 | 54.7 | |||
Yosunkaya (2010) | Turkey | Caucasian | PCR-RFLP | Mixed | 52.4 | 39.5 | |||
Cases | Controls | ||||||||
Study (Year) | N | GG | AG | AA | N | GG | AG | AA | HWE p |
Felini (2007) | 366 | 158 | 155 | 53 | 427 | 180 | 196 | 51 | 0.99 |
Cengiz (2008) | 135 | 51 | 73 | 11 | 87 | 43 | 41 | 3 | 0.42 |
Kiuru (2008) | 1,019 | 411 | 474 | 134 | 1,549 | 645 | 728 | 176 | 0.62 |
Liu (2009) | 373 | 149 | 162 | 62 | 364 | 169 | 145 | 50 | 0.35 |
Rajaraman (2010) | 350 | 142 | 164 | 44 | 478 | 205 | 201 | 72 | 0.40 |
Yosunkaya (2010) | 119 | 15 | 67 | 37 | 180 | 91 | 71 | 18 | 0.87 |
Total | 2,362 | 926 | 1,095 | 341 | 3,085 | 1,333 | 1,382 | 370 | |