Table 3 Genotype distribution of the polymorphisms in the Czech population
From: Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases
Czech sample population | |||||||
|---|---|---|---|---|---|---|---|
Gene | SNP | Allele | Genotype distribution (D-DA-A) | HWE | Dominant modela | ||
Name | ID. | (D/A) | Controls (N) | Cases (N) | Controls | OR (95% CI) | p value |
AGT | rs699 | T/C | 225-354-181 | 244-492-226 | 0.07 | 1.26 (1.01-1.57) | 0.04 |
GALNT2 | rs4846914 | A/G | 291-348-114 | 372-450-142 | 0.55 | 1.03 (0.84-1.27) | 0.76 |
GALNT2 | rs611229 | T/G | 314-358-101 | 426-427-130 | 0.95 | 0.89 (0.73-1.09) | 0.25 |
IFIH1 | rs1990760 | T/C | 282-355-109 | 360-455-151 | 0.87 | 1.04 (0.85-1.28) | 0.72 |
SLC2A2 | rs5400 | C/T | 586-161-14 | 743-217-18 | 0.45 | 1.09 (0.86-1.38) | 0.49 |
SLC2A2 | rs6785233 | T/G | 643-120-6 | 828-146-8 | 0.88 | 0.99 (0.76-1.30) | 0.95 |
SLC2A2 | rs8192675 | T/C | 392-313-66 | 491-409-73 | 0.75 | 1.03 (0.85-1.26) | 0.75 |
IGFBP2 | rs1470579 | A/C | 389-290-82 | 494-376-104 | 0.01 | 1.01 (0.83-1.23) | 0.91 |
ENPP1 | rs1044498 | A/C | 573-184-19 | 773-200-13 | 0.36 | 0.79 (0.63-1.00) | 0.05 |
ENPP1 | rs9493119 | A/G | 720-54-1 | 916-69-5 | 0.99 | 1.17 (0.80-1.71) | 0.42 |
CYP3A[x] | rs10211 | A/G | 668-97-4 | 820-150-8 | 0.81 | 1.38 (1.04-1.83) | 0.03 |
CYP3A[x] | rs667660 | A/C | 668-93-4 | 830-144-8 | 0.70 | 1.24 (0.93-1.65) | 0.14 |
MTMR9 | rs10091637 | T/C | 174-394-194 | 229-496-257 | 0.34 | 0.97 (0.77-1.23) | 0.79 |
MTMR9 | rs11250127 | A/G | 105-376-290 | 150-431-388 | 0.33 | 0.87 (0.65-1.15) | 0.32 |
ABCA1 | rs4149268 | G/A | 309-363-94 | 398-458-119 | 0.42 | 1.02 (0.83-1.25) | 0.87 |
GAD2 | rs2236418 | A/G | 529-219-22 | 667-276-31 | 0.91 | 0.93 (0.75-1.15) | 0.51 |
GAD2 | rs2839670 | C/A | 526-217-22 | 672-277-35 | 0.95 | 0.94 (0.76-1.16) | 0.57 |
GAD2 | rs6482538 | A/G | 648-120-6 | 812-164-8 | 0.86 | 1.03 (0.80-1.35) | 0.80 |
GAD2 | rs7076544 | A/G | 520-230-20 | 645-304-34 | 0.36 | 1.02 (0.82-1.25) | 0.88 |
GAD2 | rs8190748 | A/G | 400-310-55 | 501-395-85 | 0.63 | 0.98 (0.80-1.19) | 0.81 |
ERBB3 | rs11171739 | T/C | 341-301-121 | 447-354-162 | 0.0001 | Â | Â |
KCTD10 | rs7298565 | G/A | 158-349-248 | 185-449-344 | 0.09 | 1.19 (0.93-1.53) | 0.16 |
CYP19A1 | rs12592797 | C/A | 623-121-7 | 798-170-9 | 0.68 | 1.24 (0.95-1.61) | 0.12 |
CYP19A1 | rs2445761 | A/G | 275-352-130 | 353-456-148 | 0.34 | 1.00 (0.82-1.23) | 0.98 |
CYP19A1 | rs2446405 | T/A | 527-218-21 | 672-279-29 | 0.79 | 1.11 (0.90-1.38) | 0.33 |
BBS4 | rs7178130 | A/G | 280-366-110 | 388-454-129 | 0.59 | 0.88 (0.72-1.08) | 0.21 |
NCP1 | rs891286 | C/A | 145-364-203 | 194-471-304 | 0.43 | 1.09 (0.84-1.40) | 0.52 |