Plot of Fay-Wu’s H (a) and plot of the Standardized Integrated Haplotype Score (|iHS|) (b). Estimates for the SNPs that were associated with CRC in the Czech population. Comparison of the African (YRI), European (CEU) and East Asian (ANS) population. All estimates refer to SNPs that are linked to the genotyped SNPs because direct values were not available for the genotyped SNPs. * indicate values that provide conclusive evidence for natural selection [12, 15, 37].