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Table 5 Variance-components and hazard ratio estimates for age-at-onset of regular cigarette use in Brazilian families.

From: Genetic analyses of smoking initiation, persistence, quantity, and age-at-onset of regular cigarette use in Brazilian families: the Baependi Heart Study

Model No heterogeneity Heterogeneity in variance components by gender
  Hazard ratio Variance components Hazard ratio Variance components
  Sex σ2 g σ2 f Sex σ2 g,m σ2 g,f σ2 f
Polygenic 0.43*** 0.58   0.43*** 0.21 0.40  
   (0.33-0.91)    (0.01-0.54) (0.11-0.78)  
Polygenic and shared family 0.43*** 0.37 0.17 0.42*** 0.03 0.28 0.25
   (0.14-0.70) (0.05-0.39)   (0.00-0.35) (0.01-0.65) (0.12-0.48)
  1. ***p ≤ 0.001; σ2 g: polygenic variance estimate; σ2 g,m: polygenic variance estimate for males; σ2 g,f: polygenic variance estimate for females; σ2 f: variance estimate for shared family effect.