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Table 4 Parameter estimates from heterogeneity analysis in variance-components by gender for smoking initiation.

From: Genetic analyses of smoking initiation, persistence, quantity, and age-at-onset of regular cigarette use in Brazilian families: the Baependi Heart Study

Model

Heterogeneity in variance components by gender

Selected model

 

h2 m

h2 f

σ2 g,m

σ2 e,m

σ2 g,f

σ2 e,f

Variance with heterogeneity

No covariate

0.475

0.547

1.559

1.721

0.519

0.430

genetic and environmental

age, sex, age2

0.696

0.696

0.885

0.385

0.885

0.385

no heterogeneity

  1. h2 (s.e.): heritability estimate (standard error); h2 m : heritability estimate for males; h2 f : heritability estimate for females; σ2 g,m : polygenic variance estimate for males; σ2 e,m : environmental variance estimate for males; σ2 g,f : polygenic variance estimate for females; σ2 e,f : environmental variance estimate for females.
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BMC Medical Genetics

ISSN: 1471-2350

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