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Table 3 Regions of clustered allelic homozygosity

From: High-resolution SNP array analysis of patients with developmental disorder and normal array CGH results

Chromosome Band Appoximate range (Kb) Frequency patients (n = 70) Frequency normals (n = 19)
1 p33-p32.3 48 700–53 300 47.7% 47.7%
1 q21.1-q21.2 145 800–148 500 49% 50%
2 q21.2-q21.3 134 334–136 693 42% 58%
3 p21.31-p21.1 46 500–52 500 71% 68%
4 p15.1 31 838–34 524 60% 57%
8 q22.2 99 200–101 200 47% 63%
8 p11.21-p11.1 41 870–43 270 49% 47%
8 q11.1-q11.21 47 040–49 000 46% 68%
10 p11.21 36 720–38 490 43% 31%
10 q22.2-q22.2 73 200–76 460 44% 31%
12 q21.32-q21.33 85 850–89 100 47% 47%
12 q24.11-q24.13 108 600–111 600 55% 68%
14 q23.3-q24.1 65 500–67 100 62% 73%
15 q12-q13.1 25 400–27 200 71% 68%
15 q15.1-q21.1 40 100–43 730 64% 84%
15 q23-q24.1 69 300–71 700 41% 15%
16 p11.2-p11.1 33 394–34 550 62% 68%
16 q11.2-q12.1 45 092–47 450 64% 63%
16 q21-q22.1 64 850–67 100 48% 57%
17 q22-q23.2 54 610–56 850 67% 68%
20 q11.22-q11.23 31 910–35 500 68% 42%
  1. The table presents the frequency (> 40%) of clustered regions of allelic homozygosity in the patient cohort (n = 70, including in-house reference) compared to the unaffected relatives (n = 19). Kilobase range according to Genome build 19 (NCBI 37).