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Table 3 Regions of clustered allelic homozygosity

From: High-resolution SNP array analysis of patients with developmental disorder and normal array CGH results

Chromosome

Band

Appoximate range (Kb)

Frequency patients (n = 70)

Frequency normals (n = 19)

1

p33-p32.3

48 700–53 300

47.7%

47.7%

1

q21.1-q21.2

145 800–148 500

49%

50%

2

q21.2-q21.3

134 334–136 693

42%

58%

3

p21.31-p21.1

46 500–52 500

71%

68%

4

p15.1

31 838–34 524

60%

57%

8

q22.2

99 200–101 200

47%

63%

8

p11.21-p11.1

41 870–43 270

49%

47%

8

q11.1-q11.21

47 040–49 000

46%

68%

10

p11.21

36 720–38 490

43%

31%

10

q22.2-q22.2

73 200–76 460

44%

31%

12

q21.32-q21.33

85 850–89 100

47%

47%

12

q24.11-q24.13

108 600–111 600

55%

68%

14

q23.3-q24.1

65 500–67 100

62%

73%

15

q12-q13.1

25 400–27 200

71%

68%

15

q15.1-q21.1

40 100–43 730

64%

84%

15

q23-q24.1

69 300–71 700

41%

15%

16

p11.2-p11.1

33 394–34 550

62%

68%

16

q11.2-q12.1

45 092–47 450

64%

63%

16

q21-q22.1

64 850–67 100

48%

57%

17

q22-q23.2

54 610–56 850

67%

68%

20

q11.22-q11.23

31 910–35 500

68%

42%

  1. The table presents the frequency (> 40%) of clustered regions of allelic homozygosity in the patient cohort (n = 70, including in-house reference) compared to the unaffected relatives (n = 19). Kilobase range according to Genome build 19 (NCBI 37).