Single nucleotide polymorphisms in thymic stromal lymphopoietin gene are not associated with allergic rhinitis susceptibility in Chinese subjects

Table 5 Diplotype analysis of common haplotypes near TSLP gene with AR risk

Block	0-copy		1-copy logistic regression			2-copy logistic regression			P (2 df)^b
Block	AR/C	OR (95%CI)	AR/C	P^a	OR (95%CI)	AR/C	P^a	OR (95%CI)	P (2 df)^b
Block1: rs12654933-rs11466741-rs13156086
CCA	85/75	1.000 (referent)	167/144	0.583	1.118 (0.750-1.667)	116/106	0.770	1.066 (0.695-1.633)	0.947
CTA	332/294	1.000 (referent)	33/30	0.709	0.902 (0.526-1.548)	3/1	0.414	2.606 (0.262-25.927)	0.676
CTC	208/178	1.000 (referent)	136/126	0.561	0.907 (0.653-1.260)	24/21	0.739	0.896 (0.468-1.713)	0.884
ACA	270/240	1.000 (referent)	86/78	0.869	1.031 (0.714-1.491)	12/7	0.763	1.164 (0.434-3.125)	0.668
Block2: rs6886755-rs252706
GG	67/60	1.000 (referent)	171/147	0.888	1.032 (0.667-1.595)	130/118	0.796	0.942 (0.600-1.480)	0.946
GA	164/149	1.000 (referent)	156/132	0.436	1.143 (0.817-1.600)	48/44	0.678	1.110 (0.679-1.815)	0.893
TG	318/279	1.000 (referent)	47/45	0.342	0.800 (0.505-1.267)	3/1	0.423	2.558 (0.257-25.465)	0.629

AR = Allergic rhinitis subjects; C = control subjects.
a. P values from unconditional logistic regression analyses, adjusted for age and gender.
b. Global P values [2 degrees of freedom (df)]: diplotype frequencies in cases and controls were compared using a χ2 test with 2 df.

ISSN: 1471-2350