TY - JOUR AU - Reznichenko, Anna AU - Böger, Carsten A. AU - Snieder, Harold AU - van den Born, Jacob AU - de Borst, Martin H. AU - Damman, Jeffrey AU - van Dijk, Marcory CRF AU - van Goor, Harry AU - Hepkema, Bouke G. AU - Hillebrands, Jan-Luuk AU - Leuvenink, Henri GD AU - Niesing, Jan AU - Bakker, Stephan JL AU - Seelen, Marc AU - Navis, Gerjan PY - 2012 DA - 2012/09/05 TI - UMOD as a susceptibility gene for end-stage renal disease JO - BMC Medical Genetics SP - 78 VL - 13 IS - 1 AB - In recent genetic association studies, common variants including rs12917707 in the UMOD locus have shown strong evidence of association with eGFR, prevalent and incident chronic kidney disease and uromodulin urinary concentration in general population cohorts. The association of rs12917707 with end-stage renal disease (ESRD) in a recent case-control study was only nominally significant. SN - 1471-2350 UR - https://doi.org/10.1186/1471-2350-13-78 DO - 10.1186/1471-2350-13-78 ID - Reznichenko2012 ER -