Table 4 Allelic distributions and related OR values
| Â | FPN1-8CG | HFEH63D | HFEC282Y | HEPC-582AG | TFP570S | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Allele (%) | C | G | H | D | C | Y | A | G | P | S |
All subjects (n=828) | 629 (76.0) | 199 (24.0) | 689 (83.2) | 139 (16.8) | 802 (96.86) | 26 (3.14) | 585 (70.6) | 243 (29.3) | 678 (81.9) | 150 (18.1) |
OR (95%CI) | 1.52 (1.2-1.93) | 1.23 (0.94-1.6) | 0.76 (0.45-1.27) | 1.30 (1.05-1.62) | 1.04 (0.81-1.34) | |||||
P uncorrected | <0.0001 | NS | NS | 0.020 | NS | |||||
(P corrected) | (<0.002) | (NS) | (NS) | (NS) | (NS) | |||||
RR (n=546) | 416 (76.2) | 130 (23.8) | 457 (83.7) | 89 (16.3) | 532 (97.4) | 14 (2.6) | 402 (73.6) | 144 (26.4) | 453 (83.0) | 93 (17.0) |
OR (95%CI) | 1.5 (1.15-1.95) | 1.18 (0.88-1.6) | 0.61 (0.33-1.16) | 1.12 (0.88-1.44) | 0.97 (0.73-1.29) | |||||
P uncorrected | 0.004 | NS | NS | NS | NS | |||||
(P corrected) | (NS) | (NS) | (NS) | (NS) | (NS) | |||||
PP + SP (n=282) | 213(75.5) | 69 (24.5) | 232 (82.3) | 50 (17.7) | 270 (96.86) | 12 (3.14) | 183 (64.9) | 99 (35.1) | 225 (79.8) | 57 (20.2) |
OR (95%CI) | 1.55 (1.12-2.15) | 1.31 (0.91-1.88) | 1.04 (0.53-2.03) | 1.7 (1.27-2.27) | 1.19 (0.85-1.68) | |||||
P uncorrected | 0.010 | NS | NS | <0.0001 | NS | |||||
(P corrected) | (NS) | (NS) | (NS) | (<0.002) | (NS) | |||||
OR 1 (95%CI) | 1.03 (0.74-1.45) | 1.10 (0.75-1.61) | 1.7 (0.8-3.7) | 1.51 (1.11-2.06) | 1.23 (0.86-1.78) | |||||
P uncorrected | NS | NS | NS | 0.010 | NS | |||||
(P corrected) | (NS) | (NS) | (NS) | (NS) | (NS) | |||||
Controls (n=828) | 685 (82.7) | 143 (17.3) | 711 (85.9) | 117 (14.1) | 794 (95.9) | 34 (4.1) | 628 (75.9) | 200 (24.1) | 683 (82.5) | 145 (17.5) |