Table 3 CMH top scoring SNPs in LD, approach II.
From: Data mining of high density genomic variant data for prediction of Alzheimer's disease risk
Gene (Chr.) dbSNP RS ID | Physical Position | Distance to Gene | Minor Allele (MAF) | p-value from χ2 | OR (95% CI) |
|---|---|---|---|---|---|
|  |  | APOEε4- SAMPLES |  |  |  |
ST5(11) | Â | Â | Â | Â | Â |
rs4910068 | 8830651 | intron | C (0.25) | 9.47E-05 | 1.57 (1.25-1.98) |
rs10743089 | 8744744 | intron | A (0.33) | 2.12E-05 | 1.59 (1.28-1.97) |
|  |  | APOE ε4+ SAMPLES |  |  |  |
TRPC1(3) | Â | Â | Â | Â | Â |
rs4259003 | 144006245 | intron | A (0.21) | 6.82E-05 | 2.36 (1.53-3.64) |
rs9784320 | 144024724 | intron | C (0.25) | 9.68E-04 | 1.87 (1.28-2.71) |
rs2033912 | 143999057 | intron | T (0.22) | 1.71E-03 | 1.86 (1.26-2.75) |
rs891159 | 81526843 | intron | C (0.24) | 2.40E-05 | 2.34 (1.56-3.49) |
ATG10(5) | Â | Â | Â | Â | Â |
rs1485587 | 81362798 | intron | G (0.48) | 8.11E-05 | 1.82 (1.35-2.45) |
rs4703879 | 81589571 | intron | A (0.24) | 1.01E-03 | 1.86 (1.28-2.71) |
ANO3(11) | Â | Â | Â | Â | Â |
rs1389421 | 25747721 | upstream 561825 | G (0.45) | 3.39E-06 | 2.07 (1.52-2.83) |
rs10834774 | 25715397 | upstream 594149 | C (0.20) | 4.01E-03 | 1.86 (1.21-2.85) |
rs11028909 | 25729021 | upstream 580525 | G (0.20) | 4.13E-03 | 1.84 (1.21-2.81) |
NDUFA12(12) | Â | Â | Â | Â | Â |
rs249153 | 93848520 | downstream 40719 | C (0.19) | 3.19E-06 | 1.63 (1.33-2.00) |
rs249154 | 93848687 | downstream 40552 | C (0.18) | 3.22E-05 | 1.54 (1.25-1.89) |
|  |  | APOE ε4+ and ε4- SAMPLES |  |  |  |
NISCH(3) | Â | Â | Â | Â | Â |
rs6784615 | 52481466 | intron | C (0.09) | 6.63E-07 | 2.13 (1.57-2.88) |
rs9855470 | 52468315 | intron | A (0.06) | 4.86E-05 | 2.11 (1.46-3.05) |
rs6445486 | 52481531 | intron | A (0.06) | 2.77E-04 | 1.90 (1.34-2.71) |
rs10865972 | 52466487 | intron | C (0.06) | 3.38E-04 | 1.87 (1.32-2.65) |
rs4687619 | 52493826 | intron | T (0.06) | 3.54E-04 | 1.93 (1.34-2.79) |
rs6810027 | 52499614 | intron | C (0.05) | 5.80E-04 | 1.89 (1.31-2.73) |