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Table 3 The codon usage in human cTnI (GenBank No. NM_000363) gene

From: High prevalence of Arginine to Glutamine Substitution at 98, 141 and 162 positions in Troponin I (TNNI3) associated with hypertrophic cardiomyopathy among Indians

Nt. Site

SNP Reference

Loction

Nt. change

Codon Site

Type

Codons

aa

fraction

frequency

codon usage

g.2560

rs3729711

Exon 5

G/T

68

Wild

CGG

(R)

0.24

28.436

6

Mutant

CGT

(R)

0.04

4.739

1

g.2563

Novel

Exon 5

C/A

69

Wild

CGC

(R)

0.36

42.654

9

Mutant

CGA

(R)

0.12

14.218

3

g.4797

rs3729841

Exon 7

G/A

179

Wild

GAG

(E)

0.857

85.308

10

     

Mutant

GAA

(E)

0.143

14.218

3