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Table 6 Demographic and clinical characteristics of PV patients

From: The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population

 

GCC genotype

 
 

No (n= 10)

Yes (n= 23)

Pvalue

Age, mean (SD)

63.2 (12.4)

60.7 (14.0)

0.5779

Sex

   

   Female

4 (40%)

13 (56.7%)

0.4646

   Male

6 (60%)

10 (43.5%)

 

Splenomegaly

5/10 (50%)

12/23 (52.2%)

0.7413

Thrombosis

3/10 (30%)

4/20 (20%)

0.4786

Therapy requirement

9/10 (90%)

22/23 (95.7%)

0.2585

Cytogenetic abnormality

0/10 (0%)

3/23 (13%)

0.1781

MF evolution

3/10 (30%)

3/23 (13%)

0.0924

AML evolution

1/10 (10%)

3/23 (13%)

0.7614

Survival, median (SD)

3427 (2336)

2840 (2822)

0.7583

  1. P value is obtained from multivariate analysis.