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Table 1 Minor allele frequency of SNPs from the JAK2 locus in PV

From: The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population

No. SNP Minor alleles in PV (n= 28) Minor alleles in control (n= 28) Pvalue* (Chi square test) Odds ratio (95% CI)
   No Yes (homo/hetero) % No Yes (homo/hetero) %   
1 rs10974944 (c→g) 7 21 (15/6) 75 17 11 (3/8) 39.2 0.0069 4.64 (1.49-14.55)
12 rs12686652 (c→g) 6 22 (21/1) 78.6 14 14 (5/9) 50 0.0257 3.67 (1.14-11.79)
13 rs12335546(c→t) 6 22 (21/1) 78.6 19 9 (1/8) 32.1 0.0005 7.74 (2.33-25.75)
19 rs4495487 (t→c) 7 21 (21/0) 75 23 5 (3/2) 17.8 < 0.0001 13.8 (3.79-50.21)
22 rs1028730 (g→a) 6 22 (21/1) 78.5 19 9 (2/7) 32.1 0.0005 7.74 (2.33-25.75)
24 rs12343867(t→c) 7 21 (21/0) 75 17 11 (4/9) 39.3 0.0069 4.64 (1.48-14.55)
  1. * P values were calculated by the cases having minor alleles (homozygous and heterozygous) and cases without minor alleles.