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Figure 2 | BMC Medical Genetics

Figure 2

From: The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population

Figure 2

Comparison of hematological features in ET and PV patients divided by JAK2 V617F mutational status and/or germline genetic variation (GCC genotype). (A) White blood cell (WBC) counts were significantly elevated in patients with JAK2 V617F-positive ET, regardless of GCC genotype (p = 0.0399). (B) Hemoglobin (Hb) levels were significantly elevated in ET patients having both JAK2 V617F and GCC genotype compared to those showing the GCC genotype but lacking JAK2 V617F (p = 0.002). (C) There was no significant difference in platelet count among ET groups. (D) Leukocyte count in PV patients. (E) Hemoglobin levels in PV patients. (F) Platelet count was significantly elevated in PV patients without the GCC genotype (p = 0.015).

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BMC Medical Genetics

ISSN: 1471-2350

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