Table 5 Risk of IL17A plymorphisms for gene methylation in the subjects older than 60 years old

 IL17A -197 G > A

GG

GA

AA

unknown

A carrier vs. GG; OR (95%CI)

p value

 unmethylated (83)

38

39

6

0

reference

-

 methylated (143)

46

79

18

0

1.80 (1.01-3.19)

0.046

 IL17A *1249 C > T

CC

CT

TT

unknown

T carrier vs. CC; OR (95%CI)

p value

 unmethylated (83)

63

15

5

0

reference

-

 methylated (143)

124

13

5

1

0.463 (0.224-0.959)

0.038

DAPK

 IL17A -197 G > A

GG

GA

AA

unknown

A carrier vs. GG; OR (95%CI)

p value

 unmethylated (103)

44

50

9

0

reference

-

 methylated (123)

40

68

15

0

1.57 (0.897-2.75)

0.11

 IL17A *1249 C > T

CC

CT

TT

unknown

T carrier vs. CC; OR (95%CI)

p value

 unmethylated (103)

79

19

5

0

reference

-

 methylated (123)

108

9

5

1

0.427 (0.204-0.893)

0.024

CDH1

 IL17A -197 G > A

GG

GA

AA

unknown

A carrier vs. GG; OR (95%CI)

p value

 unmethylated (145)

60

71

14

0

reference

-

 methylated (81)

24

47

10

0

1.76 (0.958-3.22)

0.068

 IL17A *1249 C > T

CC

CT

TT

unknown

T carrier vs. CC; OR (95%CI)

p value

 unmethylated (145)

116

22

6

1

reference

-

 methylated (81)

71

6

4

0

0.590 (0.263-1.32)

0.20