Skip to main content

Table 2 Association test results for rs1799943 and CVD (SHARE + AP)

From: BRCA2 Variants and cardiovascular disease in a multi-ethnic study

Ethnicity

Individuals with at least one CVD event (% of total)

Individuals with no CVD events (n)

MAF (A allele) *

OR (95% CI)

P

All combined+

115 (10%)

1063

range: 0.18-0.37

0.6

0.01

Aboriginal

55 (19%)

235

0.18

0.40 (0.19-0.83)

0.007

South Asian

32 (10%)

291

0.32

0.58 (0.29-1.13)

0.10

European

20 (8%)

245

0.25

0.79 (0.35-1.78)

0.55

Chinese

8 (3%)

292

0.37

1.00 (0.35-2.86)

0.99

  1. + meta-analysis (fixed-effect model) adjusted for multiple comparisons.
  2. *MAF calculated from cases and controls combined for each ethnicity.