From: SNP-set analysis replicates acute lung injury genetic risk factors
Variable | ALI (n = 142) | Non-ALI (n = 325) | p-value |
---|---|---|---|
Age, years | 39 ± 19 | 37 ± 18 | 0.35 |
Male, n (%) | 115 (81%) | 249 (77%) | 0.30 |
African ancestry, n (%) | 61 (43%) | 161 (48%) | 0.29 |
European ancestry, n (%) | 74 (51%) | 150 (43%) | 0.14 |
Era of injury 1999 – 2003, n (%) | 85 (60%) | 160 (49%) | 0.07 |
Injury Factors | |||
Blunt trauma, n (%) | 101 (71%) | 218 (67%) | 0.39 |
ISS | 26 ± 8 | 24 ± 7 | 0.008 |
APACHE III †| 64 ± 24 | 58 ± 18 | 0.004 |
Pulmonary contusion, n (%) | 54 (38%) | 76 (24%) | 0.0013 |
Treatment Factors | |||
Total PRBC 1st 24 h, units (Range) | 3.16 (0 – 19) | 1.56 (0 – 27) | <0.001 |
Mechanical ventilation, n (%) | 142 (100%) | 238 (73%) | <0.001 |
Outcomes | |||
Mortality, n (%) | 35 (25%) | 24 (7%) | <0.001 |
Hospital length of stay, days | 22 (11 – 36) | 13 (8 – 26) | <0.001 |