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Table 1 Association between rs17401966 and HBV-derived HCC

From: No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations

cohort

sample size

cases

controls

OR

  
 

(cases/controls)

GG

AG

AA

GG

AG

AA

HWE p

(95 % CI)

P a

P het b

replication 1

179/769

13

61

105

45

261

463

0.599

1.09

0.578

 

(Japan 1)

 

(7.2)

(34.1)

(58.7)

(5.9)

(33.9)

(60.2)

 

(0.82-1.43)

  

replication 2

142/251

5

46

91

14

91

146

1

0.79

0.212

 

(Japan 2)

 

(3.5)

(32.4)

(64.1)

(5.6)

(36.2)

(58.2)

 

(0.54-1.15)

  

replication 3

164/144

17

59

88

15

55

74

0.616

0.95

0.790

 

(Korea)

 

(10.4)

(36.0)

(53.6)

(10.4)

(38.2)

(51.4)

 

(0.66-1.36)

  

replication 4

94/187

10

39

44

13

80

94

0.767

1.17

0.432

 

(Hong Kong)

 

(10.6)

(41.5)

(46.8)

(6.9)

(42.8)

(50.3)

 

(0.79-1.75)

  

Meta-analysis c

       

0.996

0.965

0.423

        

(0.84-1.18)

  
  1. aP value of fisher’s exact test for allele model.
  2. bResult of Breslow-Day test.
  3. cResults of meta-analysis were calculated by the Mantel-Haenzel method.