Reliable and rapid characterization of functional FCN2 gene variants reveals diverse geographical patterns

BMC Medical Genetics

Table 2 Observed genotypes in four FCN2 gene variants in different world populations

SNP variant		Brazilian		Nigerian		Vietnamese		Europeans
		n =176	Frequency*	n =180	Frequency*	n =172	Frequency*	n =165	Frequency*	PValue
-986 G/A	GG	47	0.27	128	0.71	135	0.77	43	0.26	<0.0001
	GA	90	0.51	49	0.27	36	0.20	69	0.42
	AA	39	0.22	3	0.02	1	0.01	53	0.32
-602 G/A	GG	116	0.66	179	0.99	162	0.92	95	0.58	<0.0001
	GA	51	0.29	1	0.01	10	0.06	64	0.39
	AA	9	0.05	0	0	0	0.00	6	0.03
-4A/G	AA	103	0.59	130	0.72	144	0.82	87	0.53	<0.0001
	AG	58	0.33	46	0.26	28	0.16	61	0.37
	GG	15	0.08	4	0.02	0	0.00	17	0.10
+6424 G/T	GG	116	0.66	116	0.64	111	0.63	126	0.76	NS
	GT	55	0.31	53	0.29	53	0.30	32	0.19
	TT	5	0.03	11	0.07	8	0.05	7	0.05

ISSN: 1471-2350