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Figure 3 | BMC Medical Genetics

Figure 3

From: Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

Figure 3

Target gene predictions for miR-1306. Twelve target genes of miR-1306 were predicted by TargetScan concerning their function in AD, brain, nervous system or other neurodegenerative diseases and graphically interrelated by Path Designer (Ingenuity). The miRNA is located in the nucleus and the predicted target genes indicated by blue arrows and blue framed ellipses are located according to their Gene Ontology either in the nucleus, cytoplasm or membrane. The functions of the target genes are denoted by grey lines and grey framed ellipses and derived from Gene Ontology or Ingenuity Expert Findings, which are substantiated by literature.

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