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Figure 2 | BMC Medical Genetics

Figure 2

From: Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

Figure 2

Conservation of the three miRNA binding sites within the ADAM10 3′UTR. The figure shows the conservation of the miR-1306 (A), miR-103 (B) and miR-107 (C) binding region (light green) between different species. The blue sequence represents the miRNA binding to the DNA of different species as listed on the left side. On the right side the conservation of the miRNA binding region (light green) from different species to human sequence is given. Nucleotide mismatches in the binding region to human binding region are marked in red. The lines and colons below the miRNA sequence show perfect nucleotide matches and G:U/T wobble pairs, respectively.

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BMC Medical Genetics

ISSN: 1471-2350

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