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Table 3 A comparison of the frequencies of HLA-DRB1*04 in primary IgAN patients and healthy controls of different cohorts

From: The genetic variants at the HLA-DRB1 gene are associated with primary IgA nephropathy in Han Chinese

Cohort

Case

Controls

P

OR

95% CI

Han Chinese in the Sichuan cohorta

0.143 (55)

0.073 (28)

2.35 × 10-3

1.541

1.130–2.100

Han Chinese in the Beijing cohorta

0.126 (236)

0.093 (392)

2.67 × 10-3

1.091

1.028–1.158

Both cohorts combinedb

0.129 (291)

0.092 (420)

8.29 × 10-5

1.381

1.178–1.619

  1. OR, odds ratio; CI, confidence interval; a Fisher’s exact test, bStratified analysis using Cochran-Mantel-Haenszel method; Tests of Homogeneity of the Odds Ratio:P = 0.057.
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BMC Medical Genetics

ISSN: 1471-2350

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