Systems analysis of inflammatory bowel disease based on comprehensive gene information

BMC Medical Genetics

Table 1 A list of drugs for Inflammatory Bowel Disease and their indications

IBD state	Category	Drug name	Indication
			US	UK	Japan
Mild	Amino-salicylate	Mesalazine	UC, CD	UC, CD	UC, CD
		Salazo-sulfapyridine	UC, CD, RA	UC, CD, RA	UC, CD, RA
		Olsalazine	UC	UC	-
		Balsalazide	UC	UC	-
Moderate	Immuno-modulators	Azathioprine	RA, GVHD	RA, SLE, DM, AICAH, PM, PV, PN, AHA ITP	GVHD, CD
		Tacrolimus	PTR	PTR	PTR, GVHD, MG, RA, LN, UC
	Corticosteroids	Budesonide (Entocort only)	CD	CD	-
		Prednisolone	RA, UC (chronic), Nephrotic Syndrome, Collagen Diseases, Fulminating SLE, Allergic Conditions, Bronchial Asthma, Acute Skin Diseases, Thrombocytopenia, Organ transplantation.
Severe	Anti-TNF antibody	Infliximab	UC, CD, RA, PS, AS	UC, CD, RA, PS, AS	UC, CD, RA, PS, AS, BD
		Adalimumab	CD, RA, PS, AS	CD, RA, PS, AS	-
		Certolizumab	CD, RA	RA	-

Abbreviations: CD Crohn's disease, UC Ulcerative colitis, RA Rheumatoid artitis, PS Psoriasis (including PS Psoriatic arthritis), AS Ankylosing spondylitis, BD Bachet disease, GVHD Graft versus host disease, SLE Systemic lupus erythematosus, DM Dermatomyosis, PM Polymyositis, AICAH Auto-immune chronic active hepatitis, PV Pemphigus vulgaris, PN Polyarteritis nodosa, AHA Auto-immune haemolytic anaemia, ITP Idiopathic thrombocytopenic purpura, MG Myasthenia gravis, LN Lupus nephritis, PTR Platelet transfusion refractoriness

ISSN: 1471-2350