Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance

Table 4 Association of rs2272495 in APPL2 with obesity-related measures in all participants

rs2272495	TT(n = 131)	CT(n = 706)	CC(n = 915)	p
	Median (interquartile range)	Median (interquartile range)	Median (interquartile range)	TT + CT VS. CC
BMI (kg/m2)	22.806 (21.197, 24.844)	23.166 (21.193, 25.398)	23.459 (21.502, 25.932)	0.015
waist circumference (cm)	77.000 (71.000, 83.000)	78.000 (71.000, 84.000)	79.000 (72.000, 86.000)	0.006
hip circumference (cm)	91.000 (87.000, 95.000)	91.500 (87.000, 96.000)	92.000 (88.000, 97.000)	0.025
WHR	0.849 (0.800, 0.898)	0.849 (0.809, 0.895)	0.857 (0.809, 0.906)	0.047

Abbreviation: BMI body mass index; WHR waist to hip ratio.
P values were assessed under a recessive model.
Obesity related measures under investigation were log transformed before analysis.
Significant values are indicated in boldface.

ISSN: 1471-2350