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Table 2 Associations of APPL2 SNPs with overweight and obesity

From: Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance

SNP Mayor/minor allele Risk allele Overweight + Obesity Normal Weight OR(95%CI) p value Empirical p value OR(95%CI) # p value # Empirical p value #
    Risk allele frequencies Genotype count 11/12/22a Risk allele frequencies Genotype count 11/12/22a       
rs1107756 T/C T 0.652 313/326/91 0.616 391/473/154 1.166(1.014-1.341) 0.031 0.128 1.160
(1.009-1.333)
0.037 0.143
rs1196768 G/A A 0.413 253/354/126 0.387 377/480/149 1.118(0.974-1.282) 0.112 0.375 1.118
(0.974-1.283)
0.113 0.376
rs3751191 C/T T 0.135 551/169/15 0.126 767/228/13 1.086(0.890-1.325) 0.416 0.868 1.088
(0.891-1.329)
0.409 0.868
rs2272495 C/T C 0.746 408/290/43 0.707 507/416/88 1.218(1.047-1.416) 0.011 0.043 1.216
(1.044-1.415)
0.012 0.052
rs10861360 C/T T 0.245 415/266/45 0.227 604/339/58 1.104(0.942-1.294) 0.220 0.611 1.099
(0.939-1.285)
0.241 0.651
  1. a11, major allele homozygotes; 12, heterozygotes; 22, minor allele homozygotes.
  2. # adjust for age and sex.
  3. Significant values are indicated in boldface.