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Table 4 Association of significant EMID2 variants with nasal polyps in ATA patients (n = 353)

From: Possible role of EMID2 on nasal polyps pathogenesis in Korean asthma patients

SNP/Haplotype MAF   Co-dominant    Dominant    Recessive   
  Polyp-positive (n = 92) Polyp-negative (n = 261) OR(95%CI) P* P corr ** OR(95%CI) P* P corr ** OR(95%CI) P* P corr **
rs6947185C > A 0.457 0.538 0.72(0.51-1.01) 0.06 - 0.86(0.50-1.50) 0.60 - 0.46(0.25-0.84) 0.01 NS
rs12538381C > T 0.109 0.094 1.18(0.69-2.05) 0.55 - 1.01(0.55-1.86) 0.99 - 10.96(1.08-111.20) 0.04 NS
rs17135512A > G 0.109 0.094 1.18(0.69-2.05) 0.55 - 1.01(0.55-1.86) 0.99 - 10.96(1.08-111.20) 0.04 NS
rs13245946C > T 0.125 0.069 1.85(1.08-3.16) 0.02 NS 1.69(0.91-3.14) 0.10 - 13.43(1.44-125.46) 0.02 NS
EMID2_BL1_ht2 0.196 0.284 0.61(0.41-0.93) 0.02 NS 0.65(0.39-1.06) 0.08 - 0.20(0.05-0.88) 0.03 NS
EMID2_BL4_ht1 0.266 0.201 1.42(0.96-2.09) 0.08 - 2.68(1.05-6.85) 0.04 NS 1.34(0.83-2.18) 0.24 -
  1. *P-values at 0.05 level of significance adjusted for initial diagnosed age, sex, smoking status, and atopy. Significant values are shown in bold.
  2. **P-values after multiple testing corrections (Meff = 42.7377).
  3. MAF, minor allele frequency; OR, odds ratio; CI, confidence interval; NS, not significant.