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Table 3 Allele Frequencies of SNPs vs. General Population

From: Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study

  Allele MAF Controls q Cases   
Marker Mn/Mj popa MAF CI p Holm MAF CI p q
rs1135840 G/C 0.43 0.432 0.40-0.47 0.954 1 0.47 0.44-0.50 0.012 0.081
rs3738136 A/G 0.06 0.046 0.03-0.06 0.109 0.543 0.054 0.04-0.07 0.432 1.000
rs1043424 C/G 0.34 0.277 0.25-0.31 < 0.001 0.001 0.26 0.23-0.29 < 0.001 < 0.001
rs2234694 C/A 0.042 0.051 0.04-0.07 0.231 0.925 0.043 0.03-0.06 0.91 1.000
rs4880 C/T 0.45 0.492 0.46-0.53 0.018 0.145 0.526 0.50-0.56 < 0.001 < 0.001
rs662 G/A 0.33 0.297 0.27-0.33 0.048 0.337 0.3 0.27-0.33 0.046 0.273
rs854560 T/A 0.38 0.347 0.31-0.38 0.056 0.337 0.359 0.33-0.39 0.171 0.854
rs705381 T/C 0.18 0.254 0.23-0.29 < 0.001 < 0.001 0.248 0.22-0.28 < 0.001 < 0.001
rs7493 G/C 0.24 0.247 0.22-0.28 0.668 1 0.225 0.20-0.25 0.261 1.000
rs12026 G/C 0.24 0.246 0.22-0.28 0.699 1 0.225 0.20-0.25 0.258 1.000
rs1052553 G/Ab 0.21 0.249 0.22-0.28 0.008 0.068 0.071 0.05-0.09 < 0.001 < 0.001
  1. MAFs of studied population (control/case) compared with the general population (MAF pop) using test of proportions. aMinor allele frequencies listed on NCBI from CEU data (CEU = Utah residents with north and western European ancestry). bNote G = H2, A = H1. Mn/Mj -Minor Allele/Major Allele; MAF = Minor Allele Frequency; CI = 95% confidence intervals for determined MAF for noted population (i.e. control or case); p = p-value (Chi-squared); q = q-values for multiple testing adjustment using Holm's method.