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Table 2 Clinical data for 22q11.2DS subjects - Psychiatric and cognitive features

From: Genotype-phenotype correlation in 22q11.2 deletion syndrome

Deletion

Age [years] Mean ±SD (N)

VIQ

PIQ

FIQ

Psychosis

ADHD

MDD

Anxiety disorders

OCD

ASDs

  

Mean ±SD (N)

  

SZ

SZaff

Psychotic dis. NOS

     

LCR A-D 3Mb (TDR)

17.39±10.1 (97)

77.5±12.6 (81)

76.2±13.6 (80)

74.2±12.5 (82)

7/80 (0.09)

1/80 (0.01)

3/80 (0.04)

36/80 (0.45)

8/80 (0.10)

32/80 (0.40)

8/80 (0.10)

3/69 (0.04)

LCR A-B (~1.5 Mb)

20.50±17.41 (4)

81.0+18.0 (3)

73.0±14.0 (3)

75.0+16.8 (3)

0

1/4 (0.25)

0

2/4 (0.50)

0

1/4 (0.25)

0

0

LCR A-C (~2 Mb)

17.00±15.56 (4)

79.7+8.5 (3)

70.0±2.0 (3)

68.8±6.5 (4)

0

0

0

3/4 (0.75)

0

2/4 (50)

0

0

LCR A-D+

11.25±2.63 (4)

79.3+11.4 (4)

75.3±12.3 (4)

75.0±10.5 (4)

0

0

0

4/4 (1.00)

1/4 (0.25)

2/4 (0.50)

1/4 (0.25)

0

LCR B-D+

20

69

55

59

0

0

1

1/1 (1.00)

0

1/1 (1.00)

0

0

  1. VIQ, PIQ and FIQ – verbal, performance and full IQ, respectively, SZ - Schizophrenia, SZaff - Schizoaffective Disorder, Psychotic dis. (NOS) - Psychotic Disorder Not Otherwise Specified, ADHD - Attention Deficit Hyperactivity Disorder, MDD- Major Depressive Disorder, OCD – Obsessive Compulsive Disorder, ASDs – autism spectrum disorders.