Figure 3

Allelic expression imbalance in patients who showed the largest allelic ratios at BCL2L13, BID and MICAL3. Data points represent log2 of the normalised allelic ratio of genomic or cDNA for each replicate. A value of 0 on the Y-axis denotes an allelic ratio of 1:1. (A) Patient 13 demonstrated a 2.82 fold greater expression of the C allele relative to the G allele (P = 0.004) at BCL2L13 SNP rs2587100, (B) patient 57 demonstrated a 2.09 fold greater expression of the T allele relative to the C allele (P = 0.001) at BID SNP rs11538, (C) patient 38 demonstrated a 5.47 fold greater expression of the T allele relative to the C allele (P = 0.001) at MICAL3 SNP rs5992854.