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Table 1 Selected SNPs associated with lung cancer *

From: Prediction of lung cancer risk in a Chinese population using a multifactorial genetic model

First author, year (reference)

SNP

Gene

Chromosomal location

Genotyping rate

Risk allele

Reported OR (95% CI) ‡

McKay, 2008 [4]

rs2736100

TERT

5p15

99.5%

C

1.18 (1.10-1.26)

McKay, 2008 [4]

rs402710†

CLPTM1L

5p15

99.6%

C

1.22 (1.13-1.32)

McKay, 2008 [4]

rs1051730

CHRNA 5, CHRNA 3

15q25

98.8%

T

1.35 (1.5-1.45)

You, 2009 [24]

rs4083914

RGS17

6q23-25

99.7%

G

1.80 (1.36-2.39)

Miki, 2010 [23]

rs4488809

TP63

3q28

100%

T

1.27 (1.14-1.41)

  1. *Characteristics of the loci from the cited genome-wide association and fine-mapping studies. CI, confidence interval; OR, odds ratio.
  2. †Rs402710 showed relatively litter LD with rs2736100 (D’ = 0.020).
  3. ‡ Odds ratio per copy of the risk allele, as reported in the cited study.