Table 3 The genotype frequency of stratified by gender among Graves’ disease patients in Taiwan

rs3806933

Female

C/C

64 (42.7)

119 (53.1)

1

C/T

77 (51.3)

80 (35.7)

1.79 (1.16, 2.77)

T/T

9 (6)

25 (11.2)

0.007 (genotype)

0.67 (0.29, 1.52)

 C/T + T/T

86 (57.3)

105 (46.9)

0.047 (dominant)

1.52 (1.00, 2.31)

C allele

205 (68.3)

318 (71.0)

1

T allele

95 (31.7)

130 (29.0)

0.44

1.13 (0.83, 1.56)

Male

C/C

19 (37.3)

21 (46.7)

1

C/T

24 (47.1)

22 (48.9)

1.21 (0.52, 2.82)

T/T

8 (15.7)

2 (4.4)

0.18 (genotype)

4.42 (0.83, 23.47)

 C/T + T/T

32 (62.7)

24 (53.3)

0.35 (dominant)

1.47 (0.65, 3.33)

C allele

62 (60.8)

64 (71.1)

1

T allele

40 (39.2)

26 (28.9)

0.13

1.59 (0.87, 2.91)

rs2289276

Female

T/T

2 (1.3)

15 (6.7)

1

C/T

60 (40.0)

75 (33.5)

6.00 (1.32, 27.27)

C/C

88 (58.7)

134 (59.8)

0.034 (genotype)

4.93 (1.10, 22.07)

 C/T + C/C

148 (98.7)

209 (93.3)

0.015 (recessive)

5.31 (1.20, 23.57)

C allele

236 (78.7)

343 (76.6)

1

T allele

64 (21.3)

105 (23.4)

0.50

0.89 (0.62, 1.26)

Male

T/T

3 (5.9)

4 (8.9)

1

C/T

17 (33.3)

15 (33.3)

1.51 (0.29, 7.87)

C/C

31 (60.8)

26 (57.8)

0.847 (genotype)

1.59 (0.33, 7.76)

 C/T + C/C

48 (94.1)

41 (91.1)

0.572 (recessive)

1.56 (0.33, 7.38)

C allele

79 (77.5)

67 (74.4)

1

T allele

23 (22.5)

23 (25.6)

0.63

0.85 (0.44, 1.65)

rs2289278

Female

C/C

80 (53.3)

148 (66.1)

1

C/G

59 (39.3)

66 (29.5)

1.65 (1.06, 2.58)

G/G

11 (7.3)

10 (4.5)

0.042 (genotype)

2.04 (0.83, 5.00)

 C/G + G/G

70 (46.7)

76 (33.9)

0.013 (dominant)

1.70 (1.12, 2.60)

C allele

219 (73.0)

362 (80.8)

1

G allele

81 (27.0)

86 (19.2)

0.012

1.56 (1.10, 2.20)

Male

C/C

34 (66.7)

29 (64.4)

1

C/G

14 (27.5)

13 (28.9)

0.92 (0.37, 2.27)

G/G

3 (5.9)

3 (6.7)

0.971 (genotype)

0.85 (0.16, 4.55)

 C/G + G/G

17 (33.3)

16 (35.6)

0.819 (dominant)

0.91 (0.39, 2.11)

C allele

82 (80.4)

71 (78.9)

1

G allele

20 (19.6)

19 (21.1)

0.80

0.91 (0.45, 1.84)