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Table 2 The association between TSLP gene haplotypes among control and GD patients

From: Thymic stromal lymphopoietin gene promoter polymorphisms and expression levels in Graves’ disease and Graves’ ophthalmopathy

Haplotype*

rs3806933

rs2289276

rs2289278

Control

GD

p value**

OR (95% CI)

Ht1

C

C

C

60

433

0.09

1.35 (0.95–1.9)

Ht2

C

C

G

37

205

0.56

0.89 (0.59–1.32)

Ht3

T

C

C

5

93

0.007

3.28 (1.31–8.21)

Ht4

T

T

C

39

200

0.27

0.8 (0.54–1.19)

Ht5

T

C

G

12

2

1 × 10−14

0.03 (0.01–0.11)

  1. * The haplotypes were identified by the Bayesian statistical method available in the program Phase 2.1.
  2. ** The chi-square test (2 × 2 table) was performed to obtain the p value. For example, the numbers of haplotypes of control and GD with Ht1 were compared with the numbers of control and GD without Ht1. A p value < 0.01 was considered as statistically significant. Only haplotype with a frequency of 0.01 or above in either cases or controls are shown.
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BMC Medical Genetics

ISSN: 1471-2350

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