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Table 1 Disease pairs with comparable genetic overlaps have highly variable values for MCS

From: Cross-pollination of research findings, although uncommon, may accelerate discovery of human disease genes

Disease pair

Genetic overlap

MCS

Parkinson Disease & Gaucher Disease

2.57%

0.064803

Fragile X Syndrome & ADHD

2.57%

0.002577

Obesity & Deafness

2.57%

0.000476

α-1 Antitrypsin Deficiency & Lung Neoplasms

2.58%

0.000996

Rheumatic Fever & Rheumatic Heart Disease

12.90%

0.170213

Hypertension & Breast Neoplasms

12.91%

0.003824

Cystic Fibrosis & Sarcoma

13.01%

0.000000

Ovarian Neoplasms & Breast Neoplasms

29.47%

0.169344

Multiple Sclerosis & Rheumatoid Arthritis

29.45%

0.027160

Spinal Muscular Atrophy & Fragile X Syndrome

29.63%

0.000000

Diabetes Mellitus & Obesity

35.70%

0.183136

Autism & ADHD

37.00%

0.003636

Myotonic Dystrophy & Fragile X Syndrome

40.00%

0.000000

Asthma & Hypersensitivity

74.71%

0.392971

Cryptococcosis & Poliomyelitis

75.00%

0.000000