Table 6 Comparison of the haplotype frequencies between the healthy subjects and the HIV/AIDS patients
Haplotypes | Healthy subjects n (freq) | HIV/AIDS patients n (freq) | Efavirenz levels (μg/mL)* | Global p-value# |
|---|---|---|---|---|
NR1I2 haplotypes [rs2472677-rs3732356-rs6785049] | ||||
C-T-A | 7 (0.025) | 6 (0.012) | 2.13 | Â |
C-T-G | 109 (0.367) | 190 (0.379) | 4.00 | Â |
C-G-G | 64 (0.216) | 114 (0.226) | 6.69 | 0.015 |
T-T-A | 16 (0.052) | 6 (0.011) | 4.94 | Â |
T-T-G | 96 (0.321) | 172 (0.343) | 4.23 | Â |
T-G-G | 6 (0.019) | 13 (0.026) | 4.55 | Â |
NR1I3 haplotypes [rs2307424-rs2502815-rs3003596] | ||||
C-C-T | 153 (0.489) | 310 (0.530) | 4.97 | Â |
C-C-C | 58 (0.187) | 122 (0.208) | 3.45 | Â |
C-T-T | 7 (0.023) | 8 (0.013) | 3.53 | 0.424 |
C-T-C | 75 (0.240) | 121 (0.207) | 3.87 | Â |
T-C-T | 14 (0.045) | 22 (0.037) | 4.42 | Â |
T-C-C | 4 (0.012) | 3 (0.005) | 1.89 | Â |