Table 4 Baseline lung function (FEV 1 ) and LTB4R SNPs in the adult asthma cohort
From: Leukotriene B4 receptor locus gene characterisation and association studies in asthma
SNP | MAF | p-value (R2) | Group (n) | Value, % (Mean ± SEM) |
|---|---|---|---|---|
LTB4R2 | ||||
*rs2332320 | 0.10 | 0.703 | 0 (210) | 92.568 ± 1.424 |
(5′UTR) | (0.001) | 1 (50) | 91.331 ± 2.918 | |
rs11158635 | 0.19 | 0.421 | 0 (168) | 93.592 ± 1.599 |
(5′UTR) | (0.007) | 1 (79) | 90.047 ± 2.331 | |
2 (11) | 89.882 ± 6.247 | |||
rs2516564 | 0.19 | 0.422 | 0 (170) | 93.529 ± 1.592 |
(5′UTR) | (0.007) | 1 (77) | 89.871 ± 2.365 | |
2 (10) | 90.412 ± 6.564 | |||
LTB4R1 | ||||
rs2224122 | 0.20 | 0.599 | 0 (166) | 93.469 ± 1.588 |
(5′UTR) | (0.004) | 1 (81) | 90.802 ± 2.274 | |
2 (12) | 90.642 ± 5.907 | |||
rs1046587 | 0.49 | 0.761 | 0 (73) | 90.804 ± 2.436 |
(3′UTR) | (0.002) | 1 (118) | 92.044 ± 1.916 | |
2 (67) | 93.409 ± 2.543 | |||
rs3181384 | 0.20 | 0.694 | 0 (167) | 93.157 ± 1.598 |
(3′UTR) | (0.003) | 1 (82) | 90.917 ± 2.281 | |
2 (12) | 90.642 ± 5.962 |