Skip to main content

Table 2 Clinical characteristics of the study cohorts

From: Leukotriene B4 receptor locus gene characterisation and association studies in asthma

 

Asthma Families

Adult Asthma Cohort

Pedigrees

Sibling 1

Sibling 2

Age (years, mean±SD)

26.2±1.6

13.3±4.4

10.3±4.6

39.24±12.31

Gender (%, Female)

50.8

54.6

53.7

65.6

Asthma (%, Doctor diagnosed)

61.6

100

100

100

FEV1 (% Predicted) (mean±SD)

ND

95.4±15.6

96.2±14.9

92.37±20.57

Positive skin prick test (%)

62.5

73.9

65.1

64.3

Eczema (%, questionnaire)

41.1

53.5

55.1

31.8

Hay fever (%, questionnaire)

50.2

64.9

47.4

64.5

Log total serum IgE (mean)

2.04

2.33

2.33

2.03

Step on BTS guidelines (%):

    

 · Step 1

19.1

24.9

23.8

13.7

 · Step 2

32.5

52.7

55.7

17.7

 · Step 3

6.1

11.6

10.2

50.9

 · Step ≥4

4.7

9.2

6.7

17.7

n

1578

370

361

299