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Figure 2 | BMC Medical Genetics

Figure 2

From: Leukotriene B4 receptor locus gene characterisation and association studies in asthma

Figure 2

Profiling LTB4R1 and LTB4R2 variants in lung and peripheral cells. PCR was used to screen for the 5′RACE variants in various cells and tissues. A common reverse PCR primer was designed in the LTB4R1 open reading frame sequence and different forward PCR primers were designed to assay for the four variants. RT- samples did not show any amplification signals (data not shown). HASM: human airway smooth muscle; HBECu: undifferentiated human bronchial epithelial cells; HBECd: differentiated human bronchial epithelial cells; PBMC: peripheral blood mononuclear cell; PMN: polymorphonuclear neutrophil; BEAS-2B: human bronchial epithelial cell line; THP-1: human acute monocytic leukemia cell line.

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