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Table 5 Effect of obesity/overweight on T2DM according to quartiles of risk allele numbers

From: The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study

Quartiles

 

T2DM

Contrrol

OR

(95% CI)

P-value

of risk alleles

 

(n = 333)

(n = 417)

   

All subjects

obese

149

94

2.78

(2.10-3.72)

< 0.0001

 

non-obese

184

323

   

Q1

obese

36

25

5.31

(2.79-10.33)

< 0.0001

(≦ 14)

non-obese

31

112

   

Q2

obese

43

26

3.59

(1.98-6.61)

< 0.0001

(15, 16)

non-obese

50

104

   

Q3

obese

40

31

1.61

(0.89-2.93)

0.11

(17, 18)

non-obese

58

69

   

Q4

obese

30

12

2.18

(0.99-5.02)

0.052

(≧ 19)

non-obese

45

38

   
  1. ORs and P-values were adjusted with age
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BMC Medical Genetics

ISSN: 1471-2350

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