Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: The Athero Gene Study

Table 3 Hazard ratios (95% confidence interval) for cardiovascular death or myocardial infarction according to quartiles of baseline sEPCR levels

	Q1	Q2	Q3	Q4	p (continuous scale)
Quartiles ranges	48 - 93	94 - 113	114 - 162	163 - 600
Patients with events/ all patients	36/418	35/418	29/419	36/418
Model 1	reference	1.00 (0.63 - 1.60)	0.85 (0.52 - 1.39)	1.03 (0.65 - 1.64)	p=0.57
		p=0.99	p=0.51	p=0.89
Model 2	reference	1.11 (0.67 - 1.83)	0.96 (0.57 - 1.62)	1.13 (0.69 - 1.87)	p=0.38
		p=0.69	p=0.87	p=0.63

Model 1: adjusted on age and sex; model 2: adjusted on age, sex, acute coronary syndrome, smoking status, body mass index, diabetes, hypertension, HDL-cholesterol, triglyceride, CRP, number of stenosed vessels, and medication use (heparin, beta-blockers, ACE-inhibitors, calcium antagonists and statins). P-value was calculated on continuous log-transformed sEPCR.

ISSN: 1471-2350