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Table 2 Genotype distribution and allele frequency for FOXA2 rs1209523 among patients with T2D and glucose-tolerant control individuals

From: The effect of FOXA2rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals

 

n (men/women)

CC (%)

CT (%)

TT (%)

MAF

(95% CI)

OR (95% CI)

P add

All individuals

       

NGT

4,875 (2,256/2,619)

4,567 (93.7)

300 (6.2)

8 (0.2)

3.2

(2.9-3.6)

0.82 (0.62-1.07)

0.1

T2D

3,507 (2,084/1,423)

3,340 (95.2)

166 (4.7)

1 (0.1)

2.4

(2.1-2.8)

  

Non-obese individuals (BMI < 30 kg/m 2 )

       

NGT

4,292 (1,999/2,293)

4,012 (93.5)

272 (6.3)

8 (0.2)

3.4

(3.0-3.8)

0.68 (0.49-0.94)

0.02

T2D

1,730 (1,096/634)

1,653 (95.5)

77 (4.5)

0 (0)

2.2

(1.8-2.8)

  
  1. Number of individuals divided into genotype groups (% in each group), and frequencies of the minor allele (MAF) in percentages. Logistic regression was used to compare allele frequencies (P add ). The odds ratios (OR) and the 95% confidence interval (CI) are given for comparison of allele frequency. NGT: Glucose-tolerant individuals, T2D: type 2 diabetic patients.
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BMC Medical Genetics

ISSN: 1471-2350

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