Skip to main content

Table 7 Analysis of haplotype-envioronment interactions under different genetic models

From: Association of polymorphisms in survivin gene with the risk of hepatocellular carcinoma in Chinese han population: a case control study

Factor

Dominant model

Recessive model

Additive model

 

β(P)

OR(95%CI)

β(P)

OR(95%CI)

β(P)

OR(95%CI)

HBsAg+

3.62(< 0.001)

37.41(16.36~85.53)

3.31(< 0.001)

27.33(13.46~55.48)

3.51(< 0.001)

33.41(15.32~72.84)

Ha

3.90(< 0.001)

49.45(6.12~399.87)

3.96(< 0.001)

52.53(6.74~409.28)

3.87(< 0.001)

47.87(5.98~382.93)

G-C-Tb

0.25(0.479)

1.06(0.65~2.53)

-0.93(0.149)

0.39(0.11~1.40)

-0.12(0.646)

0.89(0.54~1.46)

G-C-Tb*HBsAg+

-0.59(0.122)

0.56(0.26~1.17)

-0.22(0.765)

0.80 (0.19~3.38)

-0.35(0.197)

0.70(0.41~1.20)

G-C-Tb* Ha

0.18(0.596)

1.19(0.62~2.30)

0.67(0.304)

0.51(0.54~7.06)

0.21(0.414)

1.23(0.75~1.64)

AIC

1986.19

1981.85

1983.92

  1. a The medical history of viral hepatitis type B; bThe structure of G-C-T haplotypes was rs8073069-rs9904341-rs1042489; * The interaction between haplotype and environment.