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Table 7 Analysis of haplotype-envioronment interactions under different genetic models

From: Association of polymorphisms in survivin gene with the risk of hepatocellular carcinoma in Chinese han population: a case control study

Factor Dominant model Recessive model Additive model
  β(P) OR(95%CI) β(P) OR(95%CI) β(P) OR(95%CI)
HBsAg+ 3.62(< 0.001) 37.41(16.36~85.53) 3.31(< 0.001) 27.33(13.46~55.48) 3.51(< 0.001) 33.41(15.32~72.84)
Ha 3.90(< 0.001) 49.45(6.12~399.87) 3.96(< 0.001) 52.53(6.74~409.28) 3.87(< 0.001) 47.87(5.98~382.93)
G-C-Tb 0.25(0.479) 1.06(0.65~2.53) -0.93(0.149) 0.39(0.11~1.40) -0.12(0.646) 0.89(0.54~1.46)
G-C-Tb*HBsAg+ -0.59(0.122) 0.56(0.26~1.17) -0.22(0.765) 0.80 (0.19~3.38) -0.35(0.197) 0.70(0.41~1.20)
G-C-Tb* Ha 0.18(0.596) 1.19(0.62~2.30) 0.67(0.304) 0.51(0.54~7.06) 0.21(0.414) 1.23(0.75~1.64)
AIC 1986.19 1981.85 1983.92
  1. a The medical history of viral hepatitis type B; bThe structure of G-C-T haplotypes was rs8073069-rs9904341-rs1042489; * The interaction between haplotype and environment.